Predictive value of the combined triglyceride-glucose and frailty index for cardiovascular disease and stroke in two prospective cohorts.

The p for trend remained highly significant ( p < 0.001) in all models except Model 2 ( p = 0.11), which still showed elevated point estimates.

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3 A), a clear trend emerged, showing a significant escalation in stroke risk as TyGFI quartiles increased.

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In Model 3, the OR were 8.22 (95% CI 2.45–27.58, p < 0.001) for Q3 and 21.12 (95% CI 6.44–69.23, p < 0.0001) for Q4, with a significant trend across quartiles ( p for trend < 0.0001).

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