Risk Prediction and Management of BKPyV-DNAemia in Kidney Transplant Recipients: A Multicenter Analysis of Immunosuppressive Strategies.

Transpl Int · 2025 · PMC12327399 · PMID 40771589

Europe PMC DOI

hedged sentences

0.0670

closest p · 1.3× alpha

0.2600

boldest claim

The sentences

borderline significanceP = 0.067so close (0.05 < p ≤ 0.1)

CNI withdrawal was associated with borderline significance for worse survival compared to tacrolimus TDM ≥5 ng/mL ( P = 0.067).

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showed a trendP = 0.07so close (0.05 < p ≤ 0.1)

Tacrolimus TDM ≥5 ng/mL was associated with a reduced risk of graft failure (HR = 0.54, P = 0.036), while CNI withdrawal showed a trend toward a higher risk of graft failure (HR = 4.37, P = 0.07).

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did not reach statistical significancep = 0.26not close (p > 0.1)

As shown in Supplementary Figure S3 , the early-persistent subgroup exhibited a trend toward lower graft survival, although the difference did not reach statistical significance (log-rank p = 0.26).

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