A prometabolite strategy inhibits cardiometabolic disease in an ApoE-/- murine model of atherosclerosis.

JCI Insight · 2025 · PMC12333940 · PMID 40779455

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a strong trendP = 0.06so close (0.05 < p ≤ 0.1)

Carnitine palmitoyltransferase 1a ( Cpt1a ), the rate-limiting enzyme in β-oxidation, also was not significantly changed but showed a strong trend toward reduction compared with water-treated groups ( P = 0.06).

also in 5,725 other papers

showed a trendno p-value reported

Both NaBut and SerBut showed a trend toward reduction in plasma IL-1β ( Supplemental Figure 4 ).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.