Rethinking Radiation Therapy for Perineural Invasion in Oral Cancer: Does More Coverage Improve Outcomes?

Cancer Med · 2025 · PMC12340603 · PMID 40792421

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0750

boldest claim

The sentences

near statistical significancep = 0.059so close (0.05 < p ≤ 0.1)

66% for ENE‐negative), with near statistical significance ( p = 0.059).

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approaching significancep = 0.075so close (0.05 < p ≤ 0.1)

Nodal status showed an OS of 38% for N3 compared to 64% for N0, approaching significance ( p = 0.075), while ENE was associated with significantly lower OS (56% for ENE‐positive vs. 69% for ENE‐negative, p = 0.03).

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