At week 8, although not statistically significant, the DWP16001 group showed a trend toward increased water intake and urination scores compared to the placebo group, which may reflect the expected osmotic effects of SGLT2 inhibition.
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Differential glycemic effects of DWP16001 in diabetic dogs according to baseline glycemic status: a multicenter randomized controlled trial.
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The sentences
The changes in daily insulin dose did not reach statistical significance, but a trend toward insulin dose reduction was observed in the DWP16001 group.
The UPC showed a decreasing trend in the treatment group, although the change was not statistically significant.