Increased Colonic Levels of CD8+ Cytotoxic T lymphocyte-Associated Mediators in Patients With Microscopic Colitis.

Inflamm Bowel Dis · 2025 · PMC12342803 · PMID 40209110

Europe PMC DOI

hedged sentences

0.0720

closest p · 1.4× alpha

0.0720

boldest claim

The sentences

did not reach statistical significanceP = .072so close (0.05 < p ≤ 0.1)

Likewise, levels of the chemokine CCL5 (RANTES) which is stored in and degranulated from activated CD8 + T cells 20 were higher in patients with active CC and LC compared to patients with active UC, although this did not reach statistical significance ( P = .072 and P = .353, respectively).

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failed to reach statistical significanceno p-value reported

The cytotoxic protease granzyme A showed the highest levels in patients with active LC, followed by LC-HR although this failed to reach statistical significance following a Kruskal-Wallis test.

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