The cAMP responsive element modulator (CREM) transcription factor influences susceptibility to undernutrition and infection.

Crem deletion mice showed a trend toward increased VO 2 consumption and VCO 2 production ( Fig.

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The reference allele at rs58000832 was associated with WAZ in both DBC and PROVIDE (β DBC = −0.226, 95% CI DBC = −0.449–0.001, P DBC = 0.049; β PROVIDE = −0.231, 95% CI PROVIDE = −0.435–0.027, P PROVIDE = 0.027) while CBC did not reach statistical significance (β CBC = −0.147, 95% CI CBC = −0.369–0.075, P CBC = 0.197) ( Table 2 ), but the effect was consistent in direction.

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