FLOT Versus CROSS-What Is the Optimal Therapeutic Approach for Locally Advanced Adenocarcinoma of the Esophagus and the Esophagogastric Junction?

Cancers (Basel) · 2025 · PMC12345764 · PMID 40805282

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hedged sentences

0.0800

closest p · 1.6× alpha

0.9100

boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

Patients who received CROSS therapy showed a trend towards better tumor regression ( p = 0.08).

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did not reach statistical significancep = 0.91not close (p > 0.1)

However, these findings did not reach statistical significance in the log-rank test (OS p = 0.91, PFS p = 0.82, LRC p = 0.81, DC p = 0.39) (shown in Figure 1 ). 3.4.

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