Impact of Surgical Margins and Adjuvant Radiotherapy on Local Recurrence and Survival in Sacral Chordoma.

J Clin Med · 2025 · PMC12347491 · PMID 40807085

Europe PMC DOI

hedged sentences

0.0770

closest p · 1.5× alpha

0.1080

boldest claim

The sentences

showed a trendp = 0.077so close (0.05 < p ≤ 0.1)

Negative surgical margins (R0) were associated with significantly lower local recurrence rates compared to R1 and R2 resections (Fisher’s exact test, p = 0.043), and showed a trend toward improved overall survival ( p = 0.077).

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did not reach statistical significancep = 0.108not close (p > 0.1)

Adjuvant radiotherapy did not significantly reduce local recurrence ( p = 0.245); however, an increase in complication rates was observed, although this association did not reach statistical significance ( p = 0.108).

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