Comparative Effectiveness of Cognitive Behavioral Therapies in Schizophrenia and Schizoaffective Disorder: A Systematic Review and Meta-Regression Analysis.

J Clin Med · 2025 · PMC12347526 · PMID 40807143

Europe PMC DOI

hedged sentences

0.1200

closest p · 2.4× alpha

0.1200

boldest claim

The sentences

showed a trendp = 0.12not close (p > 0.1)

Meta-regression showed a trend toward lower CBT efficacy for positive symptoms with a higher SZA disorder proportion (β = +0.10 SMD per 10% increase in AP; p = 0.12), though it was not statistically significant.

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did not reach statistical significanceno p-value reported

Conclusions: Affective symptoms may reduce the effectiveness of CBT for positive symptoms in psychotic disorders, although the findings did not reach statistical significance.

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