SARS-CoV-2 infection heightens the risk of developing HPV-related carcinoma in situ and cancer.

Discov Oncol · 2025 · PMC12354360 · PMID 40813533

Europe PMC DOI

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did not reach statistical significanceno p-value reported

However, vaginal carcinoma in situ and anal carcinoma in situ, with hazard ratios of 2.180 and 1.529, did not reach statistical significance.

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a clear trendno p-value reported

These findings demonstrate a clear trend of increasing risk with greater disease severity, supporting a possible dose–response relationship between SARS-CoV-2 infection and HPV-related disease progression.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.