Effects of epigallocatechin gallate on ischemia-reperfusion injury: an experimental study in rats.

Ulus Travma Acil Cerrahi Derg · 2025 · PMC12363147 · PMID 40765189

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

did not reach statistical significancep=0.054so close (0.05 < p ≤ 0.1)

In this context, an apparent decrease in TAS levels was observed in the IRI group, although it did not reach statistical significance (Dunn-Sidak test: p=0.054) ( Table 2 ).

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an increasing trendno p-value reported

ls in guinea pigs with ischemic myocardial dysfunction.[ 31 ] Additionally, green tea extract and EGCG were shown to reduce nitrotyrosine formation, a marker of ONOO- generation, in the intestine and kidney.[ 12 , 32 ] In the present study, MPO levels, a marker of neutrophil infiltration, showed an increasing trend in the IRI group, which was modestly attenuated by EGCG treatment.

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a clear trendno p-value reported

Nevertheless, a clear trend of increased levels was observed in the IRI group compared to the SC group, and slight decreases were noted in response to 50 mg/kg EGCG.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.