Clinical value of fluorescence laparoscopic surgery on anastomotic leakage prevention in ultra-low rectal cancer: real-world multicenter retrospective evidence with neoadjuvant chemoradiotherapy stratification.

Tech Coloproctol · 2025 · PMC12370547 · PMID 40839222

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0790

boldest claim

The sentences

a strong trendP = 0.051so close (0.05 < p ≤ 0.1)

In subgroup analyses, FL significantly reduced AL rates in patients without nCRT (1.9% versus 7.2%, P = 0.045) and demonstrated a strong trend toward reduction in AL for patients receiving nCRT (13.0% versus 35.9%, P = 0.051).

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marginally nonsignificantP = 0.079so close (0.05 < p ≤ 0.1)

The incidence of SSAL was also notably lower in the FL group, with no cases of SSAL compared with 4.0% in the non-FL group, though this difference was marginally nonsignificant ( P = 0.079).

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did not reach statistical significanceno p-value reported

While the differences did not reach statistical significance, the FL group consistently demonstrated lower rates of perioperative complications compared with the non-FL group, suggesting a potential trend towards reduced perioperative risks with the use of fluorescent laparoscopy.

also in 45,344 other papers

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