Secreted ISG15 induced by Chlamydia trachomatis infection exerts immunomodulatory effects on IFN-γ defense and inflammation.

PLoS Pathog · 2025 · PMC12373280 · PMID 40627782

Europe PMC DOI

hedged sentence

0.0734

closest p · 1.5× alpha

0.0734

boldest claim

The sentences

showed a trendp = 0.0734so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

However, by 7 dpi, ISG15 −/− mice already showed a trend toward increased bacterial burden compared to WT mice (p = 0.0734), although the difference did not reach statistical significance ( Fig 4c ).

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