Biological Skin Substitutes in Pressure Ulcers: High-Purity Type I Collagen-Based Versus Amnion/Chorion Membrane.

Cureus · 2025 · PMC12377520 · PMID 40862036

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.2340

boldest claim

The sentences

highly significantp < 0.001actually significant

The statistical analysis confirmed a highly significant difference between treatment groups (p < 0.001), establishing that the 65% higher capillary density achieved with HPTC treatment represents a genuine therapeutic advantage rather than random variation.

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did not reach statistical significancep = 0.234not close (p > 0.1)

While the HPTC group showed numerically superior healing rates, this difference did not reach statistical significance (p = 0.234, Chi-square test).

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showed a trendno p-value reported

Kaplan-Meier survival analysis showed a trend toward faster healing in the HPTC group, although not statistically significant (log-rank p=0.156).

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