Current and Emerging Therapies for Prevention and Treatment of Bronchopulmonary Dysplasia in Preterm Infants.

Paediatr Drugs · 2025 · PMC12378787 · PMID 40374983

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did not reach statistical significanceno p-value reported

A placebo-controlled RCT investigating the effects of early post-natal vitamin C supplementation noted a trend toward a reduction in BPD that did not reach statistical significance [ 161 ].

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showed a trendno p-value reported

A recently reported double-blind, multicenter, phase II study showed a trend toward reduced incidence of severe BPD in infants born < 25 weeks GA in the treatment group [ 172 ].

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highly significantno p-value reported

Maintaining consistent purity and quality of MSC products on a large scale poses highly significant challenges [ 179 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.