Early 24-Hour Changes in Systemic Immune-Inflammation Index Predict Acute Kidney Injury and Mortality in ICU Patients.

Emerg Med Int · 2025 · PMC12380515 · PMID 40873991

Europe PMC DOI

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a decreasing trendno p-value reported

This SII_slope_24 h represents the rate of change in the immune–inflammation index (a positive slope indicating increasing inflammation and a negative slope indicating a decreasing trend).

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

Those in the top quartile of SII_max (extremely high peak inflammation) also showed a trend toward higher mortality, though this difference did not reach statistical significance in our sample.

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