Liposomal irinotecan with fluorouracil and leucovorin as salvage treatment for advanced biliary tract cancer refractory to gemcitabine and cisplatin.

Front Oncol · 2025 · PMC12381770 · PMID 40881879

Europe PMC DOI

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did not reach statistical significancep = 0.080so close (0.05 < p ≤ 0.1)

showed a trendno p-value reported

Moreover, a history of prior curative surgery showed a trend toward improved OS, although it did not reach statistical significance (HR = 0.65; 95% CI, 0.40–1.05; p = 0.080).

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