PARP Inhibition Shifts Murine Myeloid Cells Toward a More Tolerogenic Profile In Vivo.

CD11b expression was not significantly different between treatments, but CXCR2 and CD206 showed a trend toward upregulation in splenic PMN from olaparib-treated mice.

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Notably, a trend toward increased frequency of patrolling Mo was observed in the spleen following olaparib treatment, although this change did not reach statistical significance ( Figure S2F ).

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