Does BRCA Mutation Status Influence Ovarian Cancer Onset Timing and Patients' Treatment Outcomes?

Genes (Basel) · 2025 · PMC12385930 · PMID 40869932

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

a clear trendno p-value reported

However, there was a clear trend toward a better prognosis in the mutation-positive group.

also in 19,460 other papers

did not reach statistical significanceno p-value reported

The 3-year probability of maintaining a progression-free status was 22% (95% CI [7.3–65.1%]) in the group with the mutation and 14% (95% CI [6.8–27.4%]) in the group without the mutation; however, the differences did not reach statistical significance.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.