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Reliable New Biomarkers of Mitochondrial Oxidative Stress and Neuroinflammation in Cerebrospinal Fluid and Plasma from Alzheimer's Disease Patients: A Pilot Study.

Int J Mol Sci · 2025 · PMC12386766 · PMID 40869114

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showed a trendno p-value reported
Male ADd patients showed a trend towards an increase in the protein amount in comparison with SMC subjects.

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The size of the studied groups was quite small and, due to the very large interindividual variability in humans, the analyses in the present study often did not reach statistical significance, but our priority was to complete this pilot study, meant to pave the way for further works including larger sizes and, eventually, also longitudinally analyzed groups of sampled subjects.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.