Barely Significant
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Impact of Pre- and Post-Dilatation on Long-Term Outcomes After Self-Expanding and Balloon-Expandable TAVI.

J Funct Biomater · 2025 · PMC12387640 · PMID 40863302

2
hedged sentences
0.0600
closest p · 1.2× alpha
0.0700
boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)
han SEVs and the use post-dilatation is associated with lower survival, while the use of pre-dilatation did not influence survival; (3) however, in regard to the multivariable analysis, survival was impaired by complex CAD, atrial fibrillation, ICU stay, and higher creatinine, while post-dilatation showed a trend towards increased mortality ( p = 0.06), independent of the transprosthetic gradient; and (4) this study included a large number of TAVI platforms (six platforms in total) and there was no heterogeneity in the survival outcomes, while the Portico and Navitor valves were associated with a higher likelihood of permanent pacemaker implantation.

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did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)
Other valve platforms (Accurate, Boston, Portico, Evolut, Navitor) did not reach statistical significance for all-cause mortality reduction, although Portico tended toward higher risk ( p = 0.07).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.