Treatment Strategies for Patients with Mitral Regurgitation: A Meta-Analysis of Randomized Controlled Trials.

J Pers Med · 2025 · PMC12387918 · PMID 40863445

Europe PMC DOI

hedged sentences

0.2400

closest p · 4.8× alpha

0.2400

boldest claim

The sentences

did not reach statistical significancep = 0.24not close (p > 0.1)

Compared to control therapy, the reduction of the recurrence of significant (grade 3+ or 4+) MR did not reach statistical significance (RR 0.44, 95% CI 0.11–1.73; p = 0.24), while showing a significant improvement of patient functional class (RR 0.60, 95% CI 0.44–0.84, p = 0.003; Figure 2 C,D).

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showed a trendno p-value reported

Compared to surgery alone, TMVR showed a trend towards higher rates of MR recurrence as well as significantly higher rates of re-intervention.

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