Impact of Sex on Lung Function in Adult Langerhans Cell Histiocytosis.

Life (Basel) · 2025 · PMC12387952 · PMID 40868907

Europe PMC DOI

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0.0750

closest p · 1.5× alpha

0.0750

boldest claim

The sentences

did not reach statistical significancep = 0.075so close (0.05 < p ≤ 0.1)

At spirometry, women tended to report more small airway impairment with lower forced expiratory flow at 25–75% (FEF 25–75 %) and maximal expiratory flow at 25% (MEF 25 %), but the differences did not reach statistical significance compared to men ( p = 0.075 for MEF 25 % and p = 0.08 for FEF 25–75 %).

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showed a trendno p-value reported

Females showed a trend toward lower small airway indices, including maximal expiratory flow at 25 (MEF 25 %) and forced expiratory flow at 25–75% (FEF 25–75 %), though this was not statistically significant, while the residual volume-to-total lung capacity (RV/TLC) ratio was significantly higher in women.

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