ECM-based molecular subtypes define prognostic, EMT status, and therapeutic diversity in IDH-mutant gliomas.

NPJ Precis Oncol · 2025 · PMC12391556 · PMID 40866630

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did not reach statistical significanceP = 0.0567so close (0.05 < p ≤ 0.1)

showed a trendno p-value reported

Quantitative analysis revealed that ECM1 tumors exhibited significantly higher proportions of peritumoral edema ( P < 0.0001) and tumor necrosis ( P = 0.0039), while enhancement patterns showed a trend towards increased prevalence in ECM1 tumors but did not reach statistical significance ( P = 0.0567) (Fig. 5b ).

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