Enriched Shotgun Sequencing to Assess the Effects of Interventions to Reduce Antimicrobial Use in Neonatal Dairy Calves.

J Vet Intern Med · 2025 · PMC12392287 · PMID 40874630

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failed to reach statistical significanceno p-value reported

The beta‐lactam resistance class also had a numerical decrease in RA in the Post period but failed to reach statistical significance (26.7%–18.1%, q = 0.06).

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approached significanceno p-value reported

The decrease in RA in the Post period of class A beta‐lactamases on Farm 2 was largely determined by decreases in the RA of the CTX and SHV resistance groups; the former approached significance, while the latter was statistically significant (32.6%–20.7% of all beta‐lactams on Farm 2, q = 0.06; 0.6%–0% of all beta‐lactams on Farm 2, q = 0.01, respectively).

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