4-Octyl Itaconate ameliorates diesel exhaust particle-induced oxidative stress in nasal epithelial cells.

However, due to the limited sample size, these observed increases in expression did not reach statistical significance for either gene ( Figure 1F ).

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Similarly, the expression of NF-κB, a transcription factor critically involved in the regulation of apoptosis, also showed a trend toward upregulation with increasing DEP exposure.

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