Nucleotides as an Anti-Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study).

Adv Sci (Weinh) · 2025 · PMC12412603 · PMID 40433895

Europe PMC DOI

hedged sentences

0.0720

closest p · 1.4× alpha

0.0720

boldest claim

The sentences

showed a trendp = 0.072so close (0.05 < p ≤ 0.1)

Trunk Muscle Mass (TMM) also showed a trend toward improvement, with β = 0.22 kg (95% CI: ‐0.02 to 0.45, p = 0.072 for all models.

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did not reach statistical significanceno p-value reported

Although this reduction did not reach statistical significance, it indicated a potential trend toward a decrease in biological aging markers, which was consistent with the observed effect at the 19‐week endpoint.

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