Notably, patients who had been exposed to childhood maltreatment generally displayed smaller volumes compared to both the control group and the non-maltreated MDD group, but again, these differences did not reach statistical significance.
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Hippocampal subfield and amygdala volumes are associated with difficulties in emotion regulation of depressed patients with a history of childhood maltreatment.
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The sentences
While we observed a clear trend of volume decrease in the depressed patients, this difference did not achieve statistical significance.