Association between maternal glucose levels in pregnancy and offspring's metabolism and adiposity: an 18-year birth cohort study.

Although the offspring of mothers with GDM showed a trend towards an increased risk of elevated adiposity traits, most of these associations did not reach statistical significance in the fully adjusted models (ESM Table 7 ).

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Offspring of mothers with gestational diabetes mellitus showed a higher prevalence of abnormal glucose tolerance (11.86% vs 7.97%), impaired fasting glucose (1.89% vs 0.49%) and impaired glucose tolerance (10.34% vs 7.13%) than offspring of mothers with normal glucose tolerance, although these associations did not reach statistical significance in fully adjusted models, underscoring the benefit of considering maternal glucose as a continuous trait.

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