The Impact of Body Composition on Outcomes in NSCLC Patients Treated with Immune Checkpoint Inhibitors: A Systematic Review.

Cancers (Basel) · 2025 · PMC12427566 · PMID 40940861

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a significant trendno p-value reported

[ 46 ] noted that higher BMI, particularly in obese patients (BMI ≥ 25 kg/m 2 ), was associated with a 25% lower risk of disease progression (HR = 0.75; 95% CI: 0.62–0.92), with a significant trend of decreasing progression risk with increasing BMI.

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did not reach statistical significanceno p-value reported

[ 48 ] observed shorter PFS and OS in cachectic patients, but these differences did not reach statistical significance.

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