Genistein Enhances GLUT4 Expression and Translocation in the Gastrocnemius Muscle and Improves Systemic Glucose Metabolism in Ovariectomized Mice.

Data from clinical studies have shown that postmenopausal women receiving hormone replacement therapy (HRT) show a significant trend toward a decrease in the degree of insulin resistance and cumulative incidence of diabetes mellitus [ 3 ].

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While weight gain differences between E2 and OVX mice did not reach statistical significance, E2 mice demonstrated a consistent weight gain trend.

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