Importantly, patients with elevated tubular CXCL12 expression showed a trend of accelerated deterioration of kidney function (referred to as kidney progression) ( Fig. 5D ).
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Inflammatory Milieu by Crosstalk between Glomerulus and Proximal Tubular Cells in Type 2 Diabetes Mellitus Kidney Disease.
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The sentences
T2DKD human biopsy samples showed a correlation between increased tubular CXCL12 expression and poor disease prognosis, although this did not reach statistical significance.