Barely Significant
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Transcranial Direct Current Stimulation of the Temporoparietal Junction in Autism Spectrum Disorder: Results of a Phase-IIa Randomized, Double-Blind, Sham-Controlled Feasibility Study.

Autism Res · 2025 · PMC12442529 · PMID 40665956

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showed a trendno p-value reported
There were no differences in the prespecified primary outcome social responsiveness between sham and tDCS immediately after the intervention (standardized estimated effect size [ES] = 0.098; 95%‐confidence interval [95% CI] −1.043;1.240), but the sham group showed a trend for better social responsiveness at the 4 week follow‐up (ES = 1.106; 95% CI −0.054; 2.270).

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nominally significantno p-value reported
Thus, besides nominally significant group differences, differences with large effect sizes (> 0.80) are additionally reported below. 5.5 Secondary Endpoints of Efficacy—Behavior Rating Scales A positive effect of tDCS versus sham was found on the reduction of compulsive behavior captured by the parent rated RBS‐R with a medium effect size (ES = −0.590, 95% CI −1.140; −0.040; tDCS EM 2.22, SE 0.41, sham EM 3.36, SE 0.345).

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