After CPAP treatment, we observed a nonsignificant trend toward a decrease in afternoon melatonin levels (to 71.07 pg/mL, p = 0.130), which may represent normalization of the disrupted circadian rhythm pattern, although statistical significance was not reached.
While overall melatonin levels showed a trend toward reduction from 74.88 to 59.80 pg/mL (p=0.313), and afternoon melatonin concentrations decreased from 120.34 to 71.07 pg/mL (p=0.130), these changes did not reach statistical significance.
Post-treatment melatonin concentrations showed a decreasing trend, especially in the afternoon, suggesting a narrowing of the diurnal variation.