Intraoperative Dexmedetomidine Enhances Postoperative Microcirculation and Reduces Acute Kidney Injury in Cardiac Surgery: A Double-Blind Randomized Trial.

Drug Des Devel Ther · 2025 · PMC12452957 · PMID 40989246

Europe PMC DOI

hedged sentences

0.0740

closest p · 1.5× alpha

0.0740

boldest claim

The sentences

did not reach statistical significancep = 0.074so close (0.05 < p ≤ 0.1)

This difference approached but did not reach statistical significance (p = 0.074; Table 1 ).

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showed a trendno p-value reported

The perioperative trajectories of serum creatinine alongside changes in eGFR in Supplementary Figures 1 and 2 , which showed a trend toward higher eGFR in the dexmedetomidine group compared with the saline group, approaching statistical significance (group-by-time interaction p = 0.09).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.