Barely Significant
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In silico & in vitro approaches suggest osteoclastogenesis induction underlying fractures in Entrectinib-treated children.

Arch Toxicol · 2025 · PMC12454534 · PMID 40563023

Europe PMCDOI
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did not reach statistical significanceno p-value reported
Although formation of mineralized matrix showed a trend toward decreasing levels, this effect did not reach statistical significance.

also in 111,027 other papers

showed a trendno p-value reported
Secretion of osteoclastogenic factors M-CSF and sRANKL showed a trend for increase, reaching statistical significance only in the juvenile model.

also in 53,322 other papers

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