Barely Significant
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Efficacy of tocilizumab for hospitalized patients with COVID-19 pneumonia and high IL-6 levels: A randomized controlled trial.

Infection · 2025 · PMC12460590 · PMID 40232661

2
hedged sentences
0.0680
closest p · 1.4× alpha
0.0680
boldest claim

The sentences

did not reach statistical significancep = 0.068so close (0.05 < p ≤ 0.1)
Efficacy outcomes The ITT analysis revealed that the death or need for IMV percentage by day 28 was 12.9% in the participants in the tocilizumab group and 32.3% in the participants in the SOC group, although the comparison did not reach statistical significance (p = 0.068) (Table 2 ).

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showed a trendno p-value reported
The survival analysis showed a trend toward a higher accrued survival in the tocilizumab group, mainly after 10 days of randomization, however this difference did not reach statistical significance (Fig. 2 ).

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