While male PD flies showed a trend toward reduced lifespan, consistent with prior reports of α-synuclein toxicity 40 , 41 , this difference did not reach statistical significance, potentially due to environmental conditions that attenuate stress (e.g., abundant food, low density) or biological variability.
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A rationally designed microbial consortium modulates neurodegeneration in a Drosophila melanogaster model of Parkinson's disease.
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