Clinical Efficacy of Hydrogen Therapy on Acute Radiation Enteritis and Inflammatory Response in Patients with Cervical Cancer Undergoing Concurrent Chemoradiation Therapy.

38 , 39 Although the PLR values in the experimental group showed a trend toward being lower than those in the control group, this difference was not statistically significant ( P > .05), which may be related to sample size or the sensitivity of PLR values as an inflammatory marker. 40 Because a pivotal pro-inflammatory cytokine, IL-6, plays a central role in mediating acute-phase responses and inflammation. 19 This study found that IL-6 levels did not significantly increase in the experimental group after treatment, although they significantly increased in the control group ( P value < .05).

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Although the experimental group consistently exhibited lower PLR values at each time point, the differences did not reach statistical significance.

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