Barely Significant
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The Prognostic Role of IL-6 and RBP4 in Colorectal Cancer.

Biomedicines · 2025 · PMC12467132 · PMID 41007818

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hedged sentences
0.0000
closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp < 1 × 10 −16actually significant
It exhibits highly significant protein interaction enrichment ( p < 1 × 10 −16 ).

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did not reach statistical significancep = 0.0513so close (0.05 < p ≤ 0.1)
showed a trendno p-value reported
For RBP4, high expression showed a trend toward reduced survival, though it did not reach statistical significance (median overall survival (OS) of 67.30 months compared with not reached) ( p = 0.0513; HR = 1.757, 95% CI: 1.076–2.868; Figure 5 B). 3.4.

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