Among patients with high SMIM25 and COX-2 levels, a higher frequency of SD or PD was observed compared to patients with high SMIM25 but low COX-2 levels, although this difference did not reach statistical significance ( p > 0.05; Figure 7 H).
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The <i>SMIM25-COX-2</i> Axis Modulates the Immunosuppressive Tumor Microenvironment and Predicts Immunotherapy Response in Hepatocellular Carcinoma.
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showed a trendp > 0.05
Both clusters showed a trend toward association with poorer clinical outcomes ( p > 0.05; Figure 5 G).