Barely Significant
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Preliminary Evidence for Sex-Specific Trends in Probiotic Modulation of Gut Saccharibacteria in Familial Mediterranean Fever Patients: Effects of <i>Lactobacillus acidophilus</i> INMIA 9602 Er 317/402 and <i>Escherichia coli</i> M-17.

Int J Mol Sci · 2025 · PMC12469711 · PMID 41009527

Europe PMCDOI
2
hedged sentences
0.0540
closest p · 1.1× alpha
0.0540
boldest claim

The sentences

approached significancep = 0.054so close (0.05 < p ≤ 0.1)
In particular, OUT 3 showed a statistically significant reduction ( p = 0.048), while OTU 2 and OTU 4 approached significance ( p = 0.054 and p = 0.057, respectively).

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did not reach statistical significanceno p-value reported
While most changes did not reach statistical significance, probiotic-specific trends, particularly in FMF women, indicated potential sex-specific effects.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.