Development of a Raman-Based Method for the Diagnosis of People with Obstructive Sleep Apnea Syndrome: The Role of Lactic Acid.

In contrast, the AUC of the lactic acid peak shows a negative trend, although this effect is not statistically significant ( p = 0.05, coefficient β 2 = −1.15; Figure 6 b), which may suggest an increased AUC in patients with OSAS compared to CTR.

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Subsequently, a simple LM was performed, also considering the near-significant correlation between CV and the AUC of the lactic acid peak.

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The results of the ELISA of SOD3 show significant differences between the experimental groups ( Figure 5 b, Mann–Whitney test, p = 0.042): a positive trend was observed in the OSAS group compared to the CTR.

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