Second United Arab Emirates consensus guidance on the diagnosis and management of inflammatory bowel disease.

World J Gastroenterol · 2025 · PMC12476678 · PMID 41024766

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did not reach statistical significanceno p-value reported

In CORE I, budesonide MMX 9 mg achieved significantly higher remission rates (17.9%) compared to placebo (7.4%, P = 0.0143), while the 6 mg dose did not reach statistical significance.

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showed a trendno p-value reported

While higher maintenance dosing (40 mg weekly) in SERENE UC showed a trend toward improved remission at week 52, this did not reach statistical significance, and the exploratory TDM arm did not outperform fixed dosing.

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