Rituximab retreatment guided by CD27+ B-cell count vs. clinical relapse in anti-MAG polyneuropathy: a cost-effective approach with lower cumulative doses.

When comparing the two cohorts at the most recent FU, the reduction in MRC score observed in the Kim's protocol cohort showed a trend toward statistical significance compared to the relapse cohort ( p = 0.0501; Table 2 ). 3.2.2 INCAT disability scale In the relapse cohort we observed a significant reduction in INCAT scores at the FU timepoint compared to the pre-RTX scores (2.58 ± 1.17 vs. 3.21 ± 1.31; p < 0.05; Table 2 ; Figure 1 ).

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32,778 ± 29,469), although this difference did not reach statistical significance ( p = 0.083; Table 3 ; Figure 2 ) When the two cohorts are solely compared at the last FU, a p -value of 0.074 ( Table 2 ; Figure 2 ) suggests a numerically greater reduction in antibody titer in the Kim's protocol cohort than in the relapse one, albeit not reaching statistical significance.

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