Cell Type-Specific Contributions of UBE3A to Angelman Syndrome Behavioral Phenotypes.

eNeuro · 2025 · PMC12479163 · PMID 40935670

Europe PMC DOI

hedged sentences

0.0533

closest p · 1.1× alpha

0.0675

boldest claim

The sentences

showed a trendp = 0.0533so close (0.05 < p ≤ 0.1)

Corresponding with the slightly earlier and lengthened “siesta” period, Gad2-Cre:: Ube3a mFLOX/p+ mice showed a trend toward increased total sleep in the dark cycle ( Fig. 5 B ; genotype × time interaction: F (2,39) = 3.164, p = 0.0533).

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did not reach statistical significancep = 0.0675so close (0.05 < p ≤ 0.1)

7 C ; genotype × time interaction: F (10,240) = 2.202, p = 0.0184); however, overall bout durations across the light and dark cycles did not reach statistical significance ( Fig. 7 D ; main effect of genotype: F (2,48) = 2.852, p = 0.0675, genotype × time interaction: F (2,48) = 2.343, p = 0.1069).

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