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Fully ablative CO<sub>2</sub> laser therapy for rhinophyma: long-term efficacy, safety and insights from an artificial intelligence-assisted predictive model in a large cohort.

Skin Health Dis · 2025 · PMC12480734 · PMID 41035836

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hedged sentences
0.0640
closest p · 1.3× alpha
0.0640
boldest claim

The sentences

showed a trendP = 0.064so close (0.05 < p ≤ 0.1)
Higher rhinophyma grades were also strongly associated with increased patient satisfaction (aOR 4.97, 95% CI 2.79–9.48; P < 0.001) and showed a trend toward higher recurrence risk (aOR = 6.11, 95% CI: 0.92–690.69, P = 0.064).

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23 Although higher rhinophyma grade did not reach statistical significance as a predictor of recurrence, a strong directional trend was noted, reinforcing the need for long-term surveillance in severe cases.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.