Comparative effectiveness of antiviral treatment on household transmission of SARS-CoV-2: a retrospective cohort study using administrative data.

BMC Infect Dis · 2025 · PMC12482191 · PMID 41023657

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0620

boldest claim

The sentences

showed a trendp = 0.051so close (0.05 < p ≤ 0.1)

Index patients aged ≥ 61 years showed a trend toward a lower hazard of household transmission compared with those aged < 49 years (adjusted HR, 0.84; 95% CI, 0.71–1.00; p = 0.051).

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did not reach statistical significancep = 0.062so close (0.05 < p ≤ 0.1)

However, although the reduction in transmission among hospitalized patients in our study did not reach statistical significance ( p = 0.062), it may still suggest that physical isolation after symptom onset may still help prevent secondary infections.

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