The impact of systemic inflammatory markers on EGFR-mutant non-small cell lung cancer.

BMC Cancer · 2025 · PMC12495650 · PMID 41046266

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showed a trendno p-value reported

A meta-analysis of European cohorts showed a trend toward an increased risk of lung cancer, reaching statistical significance for the adenocarcinoma subtype (HR 1.55; 95% CI, 1.05–2.29) with increasing exposure to PM2.5 [ 12 ].

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did not reach statistical significanceno p-value reported

Regarding EGFRm patients, we also found a significant elevation of STAT3 protein compared to EGFRwt population while other inflammatory cytokines did not reach statistical significance.

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